Efudix cream (5 Flurouacil)

Efudix is a chemotherapy cream which when applied to areas of sun damaged skin, destroys the abnormal cells that make up these lesions.

• Wash and dry the affected areas of skin before applying Efudix
• Apply the cream with a cotton bud or gloved finger
• Apply a thin layer of cream, just sufficient to cover the affected area of skin
• Be careful when applying Efudix near to the eyes, nose or mouth
• Apply the cream as directed overleaf

Apply the cream as directed

• Do not use Efudix with any other medicated cream
• Avoid exposure of the treated areas to the sun or sun lamps whilst using the cream, when outside in the sun cover up with clothing/hat
• If you become pregnant during treatment stop using the Efudix and inform your doctor

You will be told which of the following applies to you.

• Cover the area with a layer of cling film and tape down the sides if possible
• Cover the area with a Tegaderm dressing as shown
• Do not cover the area; leave exposed to the air

During treatment the treated area of skin will probably begin to look and feel worse before it gets better. The areas treated are likely to become red, inflamed and uncomfortable and may then crust and peel. Do not stop the treatment, this is a sign that the Efudix is working.

The most common side effects may include:

• Itching
• Soreness
• Burning
• Tenderness
• Scaling
• Swelling

The side effects will begin to settle down once the treatment has finished.

Cover the area with a dry dressing, if necessary, until it is completely healed. You may be seen in Dermatology clinic again once the treatment has finished. Do not apply any more Efudix unless advised by your doctor.

Dermatology Reception

01709 424514
9am to 4:30pm, Monday to Friday

Dermatology Department

01709 424436
8am to 7pm, Monday to Friday
8:30am to 1:30pm, Saturdays and Bank Holidays

Dermatology Clinical Nurse Specialists

01709 424735